Benzo-1,3-dioxole-5-methylamine → N-(1,3-Benzodioxol-5-ylmethyl)-10-{[(4-bromophenyl)thio]acetyl}-10,11-dihydro-5H-pyrrolo[2,1-C][1,4]benzodiazepine-3-carboxamide

関与物質

反応手順

The title compound was synthesized in the manner of Example 81 from 2,2,2-trichloro-1-[10-{[(4-bromophenyl)thio]acetyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-yl]-ethanone of Example 80 and C-benzo[1,3]dioxol-5-yl-methylamine, m.p. 154-155° C. MS [(+)ESI, m/z]: 590 [M+H]+ Anal. Calcd for C29H24BrN3O4S: C, 58.99; H, 4.10; N, 7.12. Found: C, 58.96; H, 4.26; N, 7.03.

情報源と証拠