HCID 178424075, compound → HCID 178424074, compound

HRID 639416Notes

Reaction equation

HRID 639416 reaction equation
CN1CCN([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]3[N:20]=[C:19]([C:21]4[C:22]([C:26]5[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=5)=[N:23][NH:24][CH:25]=4)[CH:18]=[CH:17][N:16]=3)=[CH:10][CH:9]=2)CC1.ClC1C=CC(C2C(C3C=CN=C(NC4C=CC=C([O:58][CH2:59][CH:60]5[CH2:65][CH2:64][N:63]([CH3:66])[CH2:62][CH2:61]5)C=4)N=3)=CNN=2)=CC=1>>[CH3:66][N:63]1[CH2:64][CH2:65][CH:60]([CH2:59][O:58][C:13]2[CH:12]=[C:11]([NH:14][C:15]3[N:20]=[C:19]([C:21]4[C:22]([C:26]5[CH:27]=[CH:28][C:29]([CH3:32])=[CH:30][CH:31]=5)=[N:23][NH:24][CH:25]=4)[CH:18]=[CH:17][N:16]=3)[CH:10]=[CH:9][CH:8]=2)[CH2:61][CH2:62]1

Participants

3

Reactant 2

HCID 178424075HCID 178424075, compoundHCID 178480345HCID 178480345, compound

Product 1

HCID 178424074HCID 178424074, compound

Procedure

The title compound is prepared as described in Example 1 using ethyl-4-methylbenzoate (see Example 25) and [3-(1-methyl-piperidin-4-ylmethoxy)-phenyl]-carbamic acid tert-butyl ester (see Example 27).

Sources & evidence

ORD record
ord-5ce93895b909472ab7232c7669f64534
Source dataset
uspto-grants-2010_04
Patent number
US07691855B2

Reaction notes

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