Hydrochloric Acid → HCID 68569120, compound

Participants

Reaction Steps

[3-(1-Methyl-piperidin-4-ylmethoxy)-phenyl]-carbamic acid tert-butyl ester (1.6 g, 0.005 mol) is dissolved in 10 mL of methanol and treated with 10 mL 6 N HCl. The solution is stirred at rt over night and then heated for 4 h to 60° C. The solvent is removed under reduced pressure and the residue dried under vacuum to give a tan foam which is used without further purification. HPLC: 8.20 (System X2); [M+H]+ 221.0.

Provenance & Evidence