HCID 23385073, compound → HCID 67455592, compound

HRID 639660Notes

Reaction equation

HRID 639660 reaction equation
[CH:1]([C:4]1[N:5]=[CH:6][O:7][CH:8]=1)([CH3:3])[CH3:2].[CH2:9]([O:11][C:12](=[O:33])[N:13]([C:22]1[CH:27]=[C:26](Br)[N:25]=[C:24]([NH2:29])[C:23]=1[N+:30]([O-:32])=[O:31])[CH2:14][C:15]1[CH:16]=[N:17][C:18]([CH3:21])=[CH:19][CH:20]=1)[CH3:10]>>[CH2:9]([O:11][C:12](=[O:33])[N:13]([C:22]1[CH:27]=[C:26]([C:6]2[O:7][CH:8]=[C:4]([CH:1]([CH3:3])[CH3:2])[N:5]=2)[N:25]=[C:24]([NH2:29])[C:23]=1[N+:30]([O-:32])=[O:31])[CH2:14][C:15]1[CH:16]=[N:17][C:18]([CH3:21])=[CH:19][CH:20]=1)[CH3:10]

Participants

3

Reactant 2

HCID 23385073HCID 23385073, compoundHCID 86614483(2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester

Product 1

HCID 67455592HCID 67455592, compound

Procedure

The title compound was prepared following the example in preparation 70, using 4-isopropyl-oxazole (54 mg) and (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester (100 mg), giving the product (71 mg) as a yellow gum.

Workup

  1. customin preparation 70

Sources & evidence

ORD record
ord-5a4bc7f5a0254e668842f684c325d585
Source dataset
uspto-grants-2010_04
Patent number
US07691877B2

Reaction notes

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