HRID639665

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11052605

未命名化合物

结构：CCOC(=O)N(Cc1ccccc1)c1cc(Br)nc(N)c1[N+](=O)[O-]

HCID86614485

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)N(Cc1ccccc1)c1cc(-c2nccn2COCC[Si](C)(C)C)nc(N)c1[N+](=O)[O-]

HCID67456488

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

结构：[Cl-].[Cl-].[Pd+2].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

催化剂HCID84124

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the example in preparation 70, using 1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole (201 mg), (2-amino-6-bromo-3-nitro-pyridin-4-yl)-benzyl-carbamic acid ethyl ester (200 mg) and palladium bis(triphenylphosphine)dichloride (71 mg), giving the product (174 mg) as a yellow gum.

WORKUP

后处理

customin preparation 70

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f35d3c9b0d324b36981b54c4318a0dae
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07691877B2
来源说明: uspto-grants-2010_04

反应 SMILES

[CH3:1][Si:2]([CH3:13])([CH3:12])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[CH:8]1.[CH2:14]([O:16][C:17](=[O:37])[N:18]([C:26]1[CH:31]=[C:30](Br)[N:29]=[C:28]([NH2:33])[C:27]=1[N+:34]([O-:36])=[O:35])[CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:15]>[Cl-].[Cl-].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd+2]>[CH2:14]([O:16][C:17](=[O:37])[N:18]([C:26]1[CH:31]=[C:30]([C:8]2[N:7]([CH2:6][O:5][CH2:4][CH2:3][Si:2]([CH3:13])([CH3:12])[CH3:1])[CH:11]=[CH:10][N:9]=2)[N:29]=[C:28]([NH2:33])[C:27]=1[N+:34]([O-:36])=[O:35])[CH2:19][C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[CH3:15]