HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxazole → (2-Amino-3-nitro-6-oxazol-2-yl-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxazole | HCID 9255 | — |
| Reactant | (2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester | HCID 86614489 | — |
| Catalyst | Bis(triphenylphosphine)palladium chloride | HCID 84124 | — |
| Product | (2-Amino-3-nitro-6-oxazol-2-yl-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester | HCID 67456888 | — |
Reaction Steps
The title compound was prepared following the example in preparation 70, using oxazole (33 mg), (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(3-cyano-benzyl)-carbamic acid ethyl ester (100 mg) and palladium bis(triphenylphosphine)dichloride (33 mg), giving the product (67 mg) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691877B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-dfdb297020df4b3ba9f6f82922689f08 |
| Source note | uspto-grants-2010_04 |