HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one → Ethyl (7-oxo-4,5,6,7-tetrahydrobenzothiazol-2-yl)thiocarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one | HCID 587850 | — |
| Reactant | O-ethyl chloromethanethioate | HCID 5325481 | — |
| Reactant | HCID 178514129 | HCID 178514129 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Ethyl (7-oxo-4,5,6,7-tetrahydrobenzothiazol-2-yl)thiocarbamate | HCID 86604919 | — |
Reaction Steps
The desired thiocarbamate is obtained in analogy with the preparation of Z-13 b, starting from 101 g of 2-amino-5,6-dihydro-4H-benzothiazol-7-one (602 mmol) in 3.4 l of pyridine and 75 g of ethyl chlorothioformate (602 mmol). Yield: 84 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691888B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-917f89c8eb94433299ea45f7a0028df5 |
| Source note | uspto-grants-2010_04 |