HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile → HCID 68515191, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile | HCID 11426414 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ammonium Hydroxide | HCID 14923 | — |
| Product | HCID 68515191 | HCID 68515191 | 63.2% |
Reaction Steps
To a solution of 1-chloro-6-methoxy-4-phenylisoquinoline-3-carbonitrile (150 mg) in 20 mL absolute EtOH and 5 ml aqueous NH4OH was added 150 mg of Raney Ni. The reaction was shaken under 12 (40 psi) for 18 h. Filtration and concentration of the reaction gave 85 mg of 1-(6-methoxy-4-phenylisoquinolin-3-yl)methanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07691879B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-8d198a458a5e492499d87db898c82e9b |
| Source note | uspto-grants-2010_04 |