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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639895Generated: October 25, 2026

(R)-Solketal → 1-{[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy}-6-methoxy-4-phenylisoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639895

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-SolketalHCID 736056—
Reactant1-(Allyloxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11438474—
Product1-{[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy}-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11773705—

Reaction Steps

Following the procedure for 1-(allyloxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using (R)-(−)-2,2,-dimethyl-1,3-dioxolane-4-methanol in place of allyl alcohol, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-ce20bdae819a4a61bf9b7d3d75888e4c
Source noteuspto-grants-2010_04