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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639901Generated: October 29, 2026

3-Amino-1-propanol → 4-(3-Fluorophenyl)-1-[(3-hydroxypropyl)amino]-6-methoxyisoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-1-propanolHCID 9086—
Reactant4-(3-Fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrileHCID 11439121—
Product4-(3-Fluorophenyl)-1-[(3-hydroxypropyl)amino]-6-methoxyisoquinoline-3-carbonitrileHCID 11428086—

Reaction Steps

Following the procedure for 4-(3-fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile, using 3-amino-1-propanol in place of 2-aminoethanol, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-df5cfa8716394ecaa100dd4958cdace2
Source noteuspto-grants-2010_04