HCID 11484900, compound → HCID 11349161, compound

HRID 639902Notes

Reaction equation

HRID 639902 reaction equation
[OH:1][CH:2]([CH2:25][OH:26])[CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:7]([C:23]#[N:24])[N:6]=1.C(OC1C2C(=CC(OC)=CC=2)C(C2C=CC=C([F:49])C=2)=C(C#N)N=1)C=C>>[OH:1][CH:2]([CH2:25][OH:26])[CH2:3][O:4][C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:18]=[CH:19][CH:20]=[C:21]([F:49])[CH:22]=2)=[C:7]([C:23]#[N:24])[N:6]=1

Participants

3

Reactant 2

HCID 11484900HCID 11484900, compoundHCID 68517560HCID 68517560, compound

Product 1

HCID 11349161HCID 11349161, compound

Procedure

Following the procedure for 1-(2,3-dihydroxypropoxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using 1-(allyloxy)-6-methoxy-4-(3-fluorophenyl)isoquinoline-3-carbonitrile in place of 1-(allyloxy)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, the title compound was synthesized.

Sources & evidence

ORD record
ord-1581022a115941458268c322937fab34
Source dataset
uspto-grants-2010_04
Patent number
US07691879B2

Reaction notes

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