Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639917Generated: October 30, 2026

Piperidin-4-ol → 1-(4-Hydroxypiperidin-1-yl)-6-methoxy-4-phenylisoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639917

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidin-4-olHCID 79341—
Reactant(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11358963—
Product1-(4-Hydroxypiperidin-1-yl)-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11428343—

Reaction Steps

Following the procedure for 1-(allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using 4-hydroxypiperidine in place of allylamine, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-bfa870505ff84c33a103cfb358d9d9e9
Source noteuspto-grants-2010_04