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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 639919Generated: October 29, 2026

(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile → 1-[(3R,4R)-3,4-dihydroxypyrrolidin-1-yl]-6-methoxy-4-phenylisoquinoline-3-carbonitrile

https://huagongshe.com/reaction/639919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11358963—
Reactant(3R,4R)-pyrrolidine-3,4-diolHCID 11499204—
Product1-[(3R,4R)-3,4-dihydroxypyrrolidin-1-yl]-6-methoxy-4-phenylisoquinoline-3-carbonitrileHCID 11485225—

Reaction Steps

Following the procedure for 1-(allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using (3R,4R)-3,4-dihydroxypyrrolidine in place of allylamine, the title compound was synthesized.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07691879B2
Source datasetuspto-grants-2010_04
ORD IDord-d5fd2007d7234af9a061bec98f7b66c7
Source noteuspto-grants-2010_04