1,4-Dideoxy-1,4-iminothreitol → HCID 11291387, compound

HRID 639920Notes

Reaction equation

HRID 639920 reaction equation
C(N[C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:7]([C:23]#[N:24])[N:6]=1)C=C.[OH:25][C@@H:26]1[C@@H:30]([OH:31])[CH2:29][NH:28][CH2:27]1>>[OH:25][C@@H:26]1[C@@H:30]([OH:31])[CH2:29][N:28]([C:5]2[C:14]3[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=3)[C:8]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:7]([C:23]#[N:24])[N:6]=2)[CH2:27]1

Participants

3

Reactant 2

HCID 1461981,4-Dideoxy-1,4-iminothreitolHCID 11358963(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile

Product 1

HCID 11291387HCID 11291387, compound

Procedure

Following the procedure for 1-(allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using (3S,4S)-3,4-dihydroxypyrrolidine in place of allylamine, the title compound was synthesized.

Sources & evidence

ORD record
ord-23e2d2594dbd403fa4e6c33bcc6c5105
Source dataset
uspto-grants-2010_04
Patent number
US07691879B2

Reaction notes

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