3-Methoxypropylamine → HCID 11371109, compound

HRID 639921Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9]([NH:13][CH2:14]CO)=[N:8][C:7]([CH3:17])=[C:6]2[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[CH3:24][O:25][CH2:26][CH2:27]CN>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9]([NH:13][CH2:14][CH2:27][CH2:26][O:25][CH3:24])=[N:8][C:7]([CH3:17])=[C:6]2[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

Reactant 2

HCID 16723-Methoxypropylamine

HCID 11415597HCID 11415597, compound

Product 1

HCID 11371109HCID 11371109, compound

Procedure

Following the procedure for 2-[(6-methoxy-3-methyl-4-phenylisoquinolin-1-yl)amino]ethanol, using (in Step B) 3-methoxy-1-aminopropane in place of ethanolamine, the titled compound was synthesized.

Sources & evidence

ORD record: ord-fbaf9c312fc94c449425072e38be0e4f
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07691879B2

Reaction notes

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