p,p'-Dimethoxybenzhydryl alcohol → 4-(4,4'-Dimethoxybenzhydryl)-thiophenyl boronic acid

HRID 640634Notes

Reaction equation

HRID 640634 reaction equation
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([CH:7](O)[C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[SH:19][C:20]1C=C[C:23]([B:26]([OH:28])[OH:27])=[CH:22][CH:21]=1>CC(O)=O>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([CH:7]([C:21]2[CH:22]=[C:23]([B:26]([OH:28])[OH:27])[S:19][CH:20]=2)[C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 69768p,p'-Dimethoxybenzhydryl alcoholHCID 44318944-Mercaptophenylboronic acid

Product 1

HCID 671206874-(4,4'-Dimethoxybenzhydryl)-thiophenyl boronic acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
60 °C

Procedure

4,4′-Dimethoxybenzhydrol (2.7 g, 11 mmol) and 4-mercaptophenylboronic acid (1.54 g, 10 mmol) were dissolved in AcOH (20 mL) and heated at 60° C. for 1 h. Solvent was evaporated and the residue was dried under high vacuum. This material was used without further purification.

Workup

  1. customSolvent was evaporated
  2. customthe residue was dried under high vacuum
  3. customThis material was used without further purification

Sources & evidence

ORD record
ord-a3c022495e4e409d9b8b9a6fd0474e8f
Source dataset
uspto-grants-2010_04
Patent number
US07691902B2

Reaction notes

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