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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 640689Generated: October 29, 2026

Sodium Hydroxide → 2-Fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzonitrile

https://huagongshe.com/reaction/640689

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHydrazine hydrate (1:1)HCID 24654—
Reactant2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrileHCID 67122451—
Product2-Fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzonitrileHCID 24811739—

Reaction Steps

from compound E by reaction with hydrazine hydrate; and (d) synthesising compound D from compound ED by reaction with sodium hydroxide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07692006B2
Source datasetuspto-grants-2010_04
ORD IDord-3aa7b01040224a30a355f163d0c91621
Source noteuspto-grants-2010_04