Tin dichloride dihydrate → HCID 59256609, compound

HRID 640803Notes

Reaction equation

HRID 640803 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[C:5]([C:6]([NH2:8])=[O:7])=[C:4]([N+:12]([O-])=O)[C:3]=1[OH:15].O.[Sn](Cl)Cl>>[NH2:12][C:4]1[C:3]([OH:15])=[C:2]([Cl:1])[CH:10]=[C:9]([Cl:11])[C:5]=1[C:6]([NH2:8])=[O:7]

Participants

3

Reactant 2

HCID 43835034Tin dichloride dihydrateHCID 59256606HCID 59256606, compound

Product 1

HCID 59256609HCID 59256609, compound

Procedure

Reduction of 4,6-dichloro-3-hydroxy-2-nitrobenzamide with tin (II) chloride hydrate according to the conditions as described in Step B gave 2-amino-4,6-dichloro-3-hydroxybenzamide as a beige solid (2.5 g, 62% (2 steps)).—1H NMR (CD3OD): δ 6.69 (s, 1H).

Sources & evidence

ORD record
ord-f319d97450b74655af80fe6507058472
Source dataset
uspto-grants-2010_04
Patent number
US07692011B2

Reaction notes

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