1,1'-Carbonyldiimidazole → HCID 135412678, compound

Participants

Reaction Steps

According to the procedure described in Step C, 2-amino-4,6-dichloro-3-hydroxybenzamide and formic acid in the presence of CDI gave, after washing the crude product with MeOH, 5,7-dichloro-8-hydroxy-3H-quinazolin-4-one as a white solid (36%).—1H NMR (DMSO-d6): δ 8.12 (s, 1H), 7.55 (s, 1H); mass spectrum: m/z 229, 231, 233 (M+−1, 100%, 66%, 11%).

Provenance & Evidence