Sodium Hydroxide → HCID 117777572, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the compound of Example 106 (800 mg, 2.1 mmol) in ethanol (15 ml) was added aqueous solution of NaOH (0.72 g, 18.06 mmol, 8.6 eq.) and the mixture was heated at 85° C. for 5 h. The mixture was quenched and extracted as in Example 1(d). The solvent was distilled off to afford the product in 70% yield (0.5 g).

Provenance & Evidence