反应详情

温度

100 °C

To a solution of the compound of Example 114 (4.0 g, 10.06 mmol) in ethanol (25 ml) was added 20% aqueous solution of NaOH (5 ml) and the reaction was heated at 100° C. for 2 h. The mixture was quenched and extracted as in Example 1(d). The solvent was distilled off to afford the product in 78% yield (2.8 g).

1. customThe mixture was quenched
2. extractionextracted as in Example 1(d)
3. distillationThe solvent was distilled off
4. customto afford the product in 78% yield (2.8 g)