Sodium Hydroxide → 3-(5-(1H-pyrazol-1-yl)-1H-benzo[d]imidazol-1-yl)-5-(1H-pyrazol-1-yl)aniline

Participants

Reaction Conditions

Reaction Steps

To a solution of the compound of Example 122 (230 mg, 0.6 mmol) in ethanol (20 ml) was added aqueous solution of sodium hydroxide (192 mg, 4.8 mmol, 8.0 eq.) and the mixture was heated at 90° C. for 3 h. The mixture was quenched and extracted as in Example 1(d). The solvent was distilled off to afford the product in 73% yield (150 mg).

Provenance & Evidence