HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-2-methylbenzenesulphonyl chloride → HCID 66969435, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-2-methylbenzenesulphonyl chloride | HCID 136286 | — |
| Reactant | HCID 46213773 | HCID 46213773 | — |
| Product | HCID 66969435 | HCID 66969435 | — |
Reaction Steps
4-{[4-(5-Fluoro-2-methyl-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-benzoic acid, MS (ISP): m/e=468.9 (M−H), was prepared as described for example 14, steps 1 to 8. Step 7 was performed using 5-fluoro-2-methyl-benzenesulfonyl chloride and yielded 4-{[4-(5-fluoro-2-methyl-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-benzoic acid ethyl ester, which was hydrolyzed in step 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696200B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-b8e65fb0ab884043800c2ab9133c9961 |
| Source note | uspto-grants-2010_04 |