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HRID641293

反应详情

EQUATION

反应方程式

HRID 641293 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1cccc(OC(F)F)c1
HCID2778226

3-(Difluoromethoxy)benzenesulfonyl chloride

C7H5ClF2O3S

结构：O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(OC(F)F)c2)CCO3)cc1
HCID24762553

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cccc(OC(F)F)c2)CCO3)cc1
HCID66789153

未命名化合物

PROCEDURE

实验过程

4-{[4-(3-Difluoromethoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-benzoic acid, MS (ISP): m/e=502.9 (M−H), was prepared as described for example 14, steps 1 to 8. Step 7 was performed using 3-difluoromethoxy-benzenesulfonyl chloride and yielded 4-{[4-(3-difluoromethoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-benzoic acid ethyl ester, which was hydrolyzed in step 8.