5-Bromo-2-methoxypyridine → HCID 10426423, compound

HRID 641514Notes

Reaction equation

HRID 641514 reaction equation
[CH:1]1([N:5]2[CH2:11][CH2:10][C:9]3[CH:12]=[C:13]([OH:16])[CH:14]=[CH:15][C:8]=3[CH2:7][CH2:6]2)[CH2:4][CH2:3][CH2:2]1.Br[C:18]1[CH:19]=[CH:20][C:21]([O:24][CH3:25])=[N:22][CH:23]=1>>[CH:1]1([N:5]2[CH2:6][CH2:7][C:8]3[CH:15]=[CH:14][C:13]([O:16][C:18]4[CH:23]=[N:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=4)=[CH:12][C:9]=3[CH2:10][CH2:11]2)[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 27348955-Bromo-2-methoxypyridineHCID 100820813-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL

Product 1

HCID 10426423HCID 10426423, compound

Procedure

Title compound was prepared from 3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol (E3) and 5-bromo-2-methoxypyridine using the protocol outlined for Example 128 (E128); MS (ES+) m/e 325 [M+H]+.

Sources & evidence

ORD record
ord-8a735040a7aa4d38b916dbb1d0aa5789
Source dataset
uspto-grants-2010_04
Patent number
US07696193B2

Reaction notes

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