化工社化工社 化学情報印刷レポート · 研究参考用
tert-Butyl (2-(trifluoromethyl)phenyl)carbamate → lithium 2-(7-(trifluoromethyl)-1H-indol-2-yl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl (2-(trifluoromethyl)phenyl)carbamate | HCID 15033883 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 反応物 | HCID 68638606 | HCID 68638606 | — |
| 生成物 | lithium 2-(7-(trifluoromethyl)-1H-indol-2-yl)acetate | HCID 68638559 | — |
反応手順
The titled compound was prepared from tert-butyl 2-(trifluoromethyl)phenylcarbamate using the procedures described in Example 26, Steps 26b through 26h, except for the use of potassium tert-butoxide instead of potassium hexamethyldisilizane in step 26g. MS (ES+) detects free acid at 244 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07696205B2 |
| 出典データセット | uspto-grants-2010_04 |
| ORD ID | ord-0ea9e34240e14b308d76ffe5eb7ac2cc |
| 出典メモ | uspto-grants-2010_04 |