2-Acetylphenylboronic acid → HCID 68579044, compound

HRID 641621Notes

Reaction equation

HRID 641621 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1B(O)O)(=O)[CH3:2].[S:13]1[C:25]2C3C=CC=CC=3C=[N:17][C:16]=2[CH:15]=[CH:14]1>>[CH3:2][C:1]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[C:25]2[S:13][CH:14]=[CH:15][C:16]=2[N:17]=1

Participants

3

Reactant 2

HCID 27343092-Acetylphenylboronic acidHCID 14452371HCID 14452371, compound

Product 1

HCID 68579044HCID 68579044, compoundYield 86%

Procedure

Starting from 2-Acetylphenylboronic acid (15 g, 91 mmol) in place of 2-formylphenylboronic acid in Step 3, the title compound (12 g, 86%, m.p. 74-76° C.) was synthesized in essentially the same manner as described in Steps 1-3 for Thieno[3,2-c]isoquinoline.

Sources & evidence

ORD record
ord-fd2d08b11b3e4be9b5d1d3526bde407b
Source dataset
uspto-grants-2010_04
Patent number
US07696221B2

Reaction notes

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