HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-methylaniline → N-(4-bromo-3-methylphenyl)3-[(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)amino]thiophene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-methylaniline | HCID 23359 | — |
| Reactant | 1H-Pyrrolo[2,3-b]pyridine-3-carbaldehyde | HCID 5372812 | — |
| Reactant | N-(4-bromo-3-methylphenyl)3-aminothiophene-2-carboxamide | HCID 61091031 | — |
| Product | N-(4-bromo-3-methylphenyl)3-[(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)amino]thiophene-2-carboxamide | HCID 10252733 | — |
Reaction Steps
EXAMPLE 9 was prepared according to the procedure described in EXAMPLE 5 using N-(4-bromo-3-methylphenyl)3-aminothiophene-2-carboxamide (prepared as described in EXAMPLE 1, part 1, using 4-bromo-3-methylaniline instead of 4-trifluoromethoxyaniline) and 7-azaindole-3-carboxaldehyde (EXAMPLE 8, part 1) instead of 2-(N-methylcarbamoyl)pyridine-4-carboxaldehyde. MS (ES+): 441, 443 [MH+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696225B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-05e48d04eef4445183965ca82c93aac5 |
| Source note | uspto-grants-2010_04 |