HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 641834Generated: October 30, 2026
Lawesson's reagent → HCID 59259084, compound
https://huagongshe.com/reaction/641834
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | 1-(Propan-2-yl)-4-[4-(propan-2-yl)phenyl]-6-[(prop-2-yn-1-yl)oxy]quinazolin-2(1H)-one | HCID 10109178 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 59259084 | HCID 59259084 | — |
Reaction Steps
A suspension of 50 mg (0.139 mmol) 1-isopropyl-4-(4-isopropyl-phenyl)-6-prop-2-ynyloxy-1H-quinazoline-2-one and 56 mg (0.139 mmol) Lawesson's reagent in 2 ml benzene is heated to 70° C. overnight. The reaction mixture is extracted (water/di-chloromethane) and the organic layer is dried and evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07696216B2 |
|---|
| Source dataset | uspto-grants-2010_04 |
|---|
| ORD ID | ord-89d724460f354e0fafedad9fe7e288aa |
|---|
| Source note | uspto-grants-2010_04 |
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