Sodium Cyanate → HCID 10273916, compound

HRID 641839Notes

Reaction equation

HRID 641839 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:28]=[CH:29][CH:30]=1)[CH2:5][NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]#[CH:16])=[CH:9][C:8]=1[C:17]([C:19]1[CH:24]=[CH:23][C:22]([CH:25]([CH3:27])[CH3:26])=[CH:21][CH:20]=1)=O.[O-:31][C:32]#[N:33].[Na+]>CC(O)=O.O>[OH:1][C:2]1[CH:3]=[C:4]([CH:28]=[CH:29][CH:30]=1)[CH2:5][N:6]1[C:7]2[C:8](=[CH:9][C:10]([O:13][CH2:14][C:15]#[CH:16])=[CH:11][CH:12]=2)[C:17]([C:19]2[CH:24]=[CH:23][C:22]([CH:25]([CH3:27])[CH3:26])=[CH:21][CH:20]=2)=[N:33][C:32]1=[O:31]

Participants

5

Reactant 2

HCID 517096Sodium CyanateHCID 59259042HCID 59259042, compound

Product 1

HCID 10273916HCID 10273916, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

A solution of 3.0 g (7.51 mmol) of the product prepared in step A in 45 ml AcOH is treated with 732 mg (11.3 mmol) sodium cyanate. The dark red solution is stirred for 2 h at rt. The resulting yellow-orange suspension is diluted with water and filtered. The orange product is washed well with water and diethyl ether to yield an orange solid. m.p. 230° C.

Workup

  1. filtrationfiltered
  2. washThe orange product is washed well with water and diethyl ether
  3. customto yield an orange solid

Sources & evidence

ORD record
ord-5ba078535ee9423faffc8da7ce461994
Source dataset
uspto-grants-2010_04
Patent number
US07696216B2

Reaction notes

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