反应详情

H2SO4 (0.1 mL) was added to a solution of 3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carboxamide (130 mg, 0.41 mmol) in ethanol (4 mL) and the resulting solution was stirred at room temperature for 1 hour. Filtration and subsequent concentration afforded 20 mg (18.6%) of 3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-5-carbonitrile as a white solid.

1. filtrationFiltration and subsequent concentration