1-Bromo-3,5-dinitrobenzene → 1-Bromo-3-methoxy-5-nitrobenzene

Participants

Reaction Steps

To a solution of 1-bromo-3,5-dinitrobenzene (5 g, 20.2 mmol) in methanol (50 ml) was added sodium methoxide (1.3 g, 24.3 mmol, 1.2 eq.) and the mixture was heated to reflux for 12 h and then quenched with 10% HCl. The solid formed was filtered and dried to afford the compound in 65% yield (3 g).

Provenance & Evidence