Sodium Hydroxide → HCID 90404447, compound

HRID 64198Notes

Reaction equation

HRID 64198 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[C:5]([C:8]([O-:10])=[O:9])=[N:6][CH:7]=1.[Na+].[OH-].[Na+]>CCO>[CH3:1][C:2]1[CH:3]=[C:4]([N:11]2[N:12]=[CH:13][CH:14]=[N:15]2)[C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 90404477HCID 90404477, compound

Product 1

HCID 90404447HCID 90404447, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

(sodium 5-methyl-3-(2H-1,2,3-triazol-2-yl)picolinate). To a solution of the title compound of Step A (489 mg, 2.6 mmol) in EtOH (7 mL) was added 4 N NaOH (660 μL, 2.6 mmol). The mixture was heated at 100° C. for 24 h. The reaction mixture was concentrated in vacuo to a white solid which was used without further purification in subsequent steps. MS (ESI) mass calcd. for C9H8N4O2, 204.1. m/z found 205.0 [M+H]+.

Sources & evidence

ORD record
ord-6b8ee61330ae4e138b179f5828e23e22
Source dataset
uspto-grants-2016_09
Patent number
US09447117B2

Reaction notes

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