5-Iodoisatin → HCID 178517193, Verbindung

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Following the general method as outlined in Example 1, into a suspension of 5-iodo-1H-indole-2,3dione in acetic acid was added 2-nitrobenzohydrazide. After stirring at 100° C., the reaction mixture was cooled to rt and a yellow solid precipitated out. Filtration on a fritté, washing with AcOH, water and drying under vacuo at 60° C. overnight gave 159 mg of the title compound (73%) as a yellow solid in 99.2% purity by HPLC (Rt: 5.67, gradient of 10 min, MaxPlot detection between 230 and 400 nm).

Herkunft & Nachweise