p-(Dimethylamino)benzohydrazide → HCID 178482822, compound

HRID 642045Notes

Reaction equation

HRID 642045 reaction equation
[I:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=O.[CH3:13][N:14]([CH3:25])[C:15]1[CH:24]=[CH:23][C:18]([C:19]([NH:21][NH2:22])=[O:20])=[CH:17][CH:16]=1>C(O)(=O)C>[CH3:13][N:14]([CH3:25])[C:15]1[CH:16]=[CH:17][C:18]([C:19]([NH:21][N:22]=[C:5]2[C:4]3[C:8](=[CH:9][CH:10]=[C:2]([I:1])[CH:3]=3)[NH:7][C:6]2=[O:11])=[O:20])=[CH:23][CH:24]=1

Participants

4

Reactant 2

HCID 88019p-(Dimethylamino)benzohydrazideHCID 886955-Iodoisatin

Product 1

HCID 178482822HCID 178482822, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
100 °C

Procedure

Following the general method as outlined in Example 1, into a suspension of 5-iodo-1H-indole-2,3-dione in acetic acid was added 4-(dimethylamino)benzohydrazide. After stirring at 100° C., the reaction mixture was cooled to rt and a yellow solid precipitated out.

Workup

  1. temperaturethe reaction mixture was cooled to rt
  2. customa yellow solid precipitated out

Sources & evidence

ORD record
ord-8533fcabded5419e88d44c4df6f46cca
Source dataset
uspto-grants-2010_04
Patent number
US07696231B2

Reaction notes

Loading…