Hydrazine hydrate (1:1) → HCID 9834790, compound

Participants

Reaction Steps

To a suspension of methyl 4-(hexanoylamino)benzoate (583 mg, 2.34 mmol) in ETOH (8 mL) was added hydrazine hydrate (1.8 mL). After stirring for 15 h at reflux, the reaction mixture was cooled to rt and a white solid precipitated out. Filtration, washing with water (2×2 mL), and drying under vacuo at rt for 72 hrs gave 321 mg of the title compound (55%) as a white solid in 96.6% purity by HPLC (MaxPlot detection between 230 and 400 nm).

Provenance & Evidence