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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642179Generated: October 31, 2026

Methylparaben → Methyl 4-((6-methylpyridin-2-yl)methoxy)benzoate

https://huagongshe.com/reaction/642179

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylparabenHCID 7456—
Reactant6-Chloromethyl-2-methylpyridinium chlorideHCID 76545—
ProductMethyl 4-((6-methylpyridin-2-yl)methoxy)benzoateHCID 914666—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure E except KI (1.3 eq.) is also added from 4-hydroxy-benzoic acid methyl ester and 2-(chloromethyl)-6-methyl-pyridine hydrochloride [CAS 3099-29-4]. MS (ES+) 258.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696234B2
Source datasetuspto-grants-2010_04
ORD IDord-b695783cef3a423b88f9137f84e17478
Source noteuspto-grants-2010_04