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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642187Generated: October 27, 2026

(4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone → N,N-Dimethyl-4-[4-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidine-1-carbonyl)-phenoxymethyl]-benzamide

https://huagongshe.com/reaction/642187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11960316—
Reactant4-(chloromethyl)-N,N-dimethylbenzamideHCID 18465093—
ProductN,N-Dimethyl-4-[4-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidine-1-carbonyl)-phenoxymethyl]-benzamideHCID 11662047—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure C using (4-Hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 4-chloromethyl-N,N-dimethyl-benzamide [CAS 121083-51-0]. MS (ES+) 436.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696234B2
Source datasetuspto-grants-2010_04
ORD IDord-060051c78f8040ae9f9c2a32024dff01
Source noteuspto-grants-2010_04