HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(chloromethyl)-N,N-dimethylbenzamide → 4-[3-Fluoro-4-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidine 1-carbonyl)-phenoxymethyl]-N,N-dimethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(chloromethyl)-N,N-dimethylbenzamide | HCID 18465093 | — |
| Reactant | (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 59259534 | — |
| Product | 4-[3-Fluoro-4-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidine 1-carbonyl)-phenoxymethyl]-N,N-dimethyl-benzamide | HCID 11719417 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure C using (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 4-chloromethyl-N,N-dimethyl-benzamide [CAS 121083-51-0]. MS (ES+) 454.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-5b58860f574e48f59c3bd65c5d387aa9 |
| Source note | uspto-grants-2010_04 |