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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642197Generated: October 30, 2026

4-(Bromomethyl)pyridine hbr → [2-Fluoro-4-(pyridin-4-ylmethoxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/642197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)pyridine hbrHCID 12752219—
Reactant(2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 59259534—
Product[2-Fluoro-4-(pyridin-4-ylmethoxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11509236—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure B using (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 4-(bromomethyl)pyridine hydrobromide. MS (ES+) 384.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696234B2
Source datasetuspto-grants-2010_04
ORD IDord-ab196a5ee0aa4a9796ad841d62952ccd
Source noteuspto-grants-2010_04