HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl bromide → [2-Fluoro-4-(4-fluoro-benzyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Reactant | (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 59259534 | — |
| Product | [2-Fluoro-4-(4-fluoro-benzyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 11675720 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure B using (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and 4-fluorobenzyl bromide. MS (ES+) 401.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-418133313616485a857ba543d191c7dc |
| Source note | uspto-grants-2010_04 |