HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Chloromethyl)-4-methanesulfonylbenzene → [3-Fluoro-4-(4-methanesulfonyl-benzyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Chloromethyl)-4-methanesulfonylbenzene | HCID 123530 | — |
| Reactant | (3-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)methanone | HCID 59259532 | — |
| Product | [3-Fluoro-4-(4-methanesulfonyl-benzyloxy)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 11561679 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure C from (3-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)methanone and 4-methylsulfonylbenzyl chloride. MS (ES+) 461.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696234B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-31244feda9514444970ebeeb9acbb2e9 |
| Source note | uspto-grants-2010_04 |