Methyl 4-(pyridin-2-ylmethoxy)benzoate → [2-(S)-(2-(R)-Methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-[4-(pyridin-2-ylmethoxy)-phenyl]-methanone

Participants

Role	Name	HCID	Charge
Reactant	Methyl 4-(pyridin-2-ylmethoxy)benzoate	HCID 2416604	—
Reactant	(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine	HCID 46911921	—
Product	[2-(S)-(2-(R)-Methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-[4-(pyridin-2-ylmethoxy)-phenyl]-methanone	HCID 11603308	—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure F from 4-(Pyridin-2-ylmethoxy)-benzoic acid methyl ester and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) 380.2

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07696234B2
Source dataset	uspto-grants-2010_04
ORD ID	ord-2d1a77a3aec241afabc329dcd36c4a65
Source note	uspto-grants-2010_04