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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642208Generated: October 26, 2026

(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine → [4-(Pyridin-2-ylmethoxy)-phenyl]-(2-(R)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/642208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853151—
ReactantMethyl 4-(pyridin-2-ylmethoxy)benzoateHCID 2416604—
Product[4-(Pyridin-2-ylmethoxy)-phenyl]-(2-(R)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 11494329—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure F from 4-(Pyridin-2-ylmethoxy)-benzoic acid methyl ester and 1-[(2R)-2-pyrrolidinylmethyl]pyrrolidine [CAS 60419-23-0]. MS (ES+) 366.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696234B2
Source datasetuspto-grants-2010_04
ORD IDord-25ea42b5f6b54d00981c0423ccc671dd
Source noteuspto-grants-2010_04