Methyl 4-((6-methylpyridin-2-yl)methoxy)benzoate → [4-(6-Methyl-pyridin-2-ylmethoxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone

Participants

Role	Name	HCID	Charge
Reactant	Methyl 4-((6-methylpyridin-2-yl)methoxy)benzoate	HCID 914666	—
Reactant	(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidine	HCID 46911921	—
Product	[4-(6-Methyl-pyridin-2-ylmethoxy)-phenyl]-[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone	HCID 11668338	—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure F from 4-(6-Methyl-pyridin-2-ylmethoxy)-benzoic acid methyl ester and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) 412.3

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07696234B2
Source dataset	uspto-grants-2010_04
ORD ID	ord-39aec07da22c46a1a4382f87e89a5383
Source note	uspto-grants-2010_04