HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-((tert-butoxycarbonyl)amino)acetate → 4-Bromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-((tert-butoxycarbonyl)amino)acetate | HCID 357729 | — |
| Reactant | 4-Bromo-2-bromomethyl-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 68428064 | — |
| Product | 4-Bromo-2-[(tert-butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 68428323 | — |
Reaction Steps
Prepared in analogy to that of Example 1(c) from 4-bromo-2-bromomethyl-1,5-bis-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 643 (M+Na+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696223B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-d3bc6137fd3841a8bfeb39681fce6b7b |
| Source note | uspto-grants-2010_04 |