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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642230Generated: October 31, 2026

P-Anisidine → 5-(4-Fluoro-phenyl)-1-(4-methoxy-phenyl)-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-Acetyl-4-(4-fluorophenyl)-4-oxobutyric acid ethyl esterHCID 14173973—
Reactant5-(4-Fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 14339194—
Product5-(4-Fluoro-phenyl)-1-(4-methoxy-phenyl)-2-methyl-1H-pyrrole-3-carboxylic acid ethyl esterHCID 68428415—

Reaction Steps

Prepared in analogy to that of 5-(4-fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester from 2-[2-(4-fluoro-phenyl)-2-oxo-ethyl]-3-oxo-butyric acid ethyl ester and 4-methoxyaniline. The title compound, ESI MS (m/z): 354 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-8ea71f2aee484f138b9e142ecce17d57
Source noteuspto-grants-2010_04