Ethyl 2-((tert-butoxycarbonyl)amino)acetate → HCID 68426295, compound

HRID 642236Notes

Reaction equation

HRID 642236 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:9]([Br:17])[N:8]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[C:7]=1[CH2:25]Br)=[O:5])[CH3:2].[CH2:27]([O:29][C:30](=[O:40])[CH2:31][NH:32][C:33]([O:35][C:36]([CH3:39])([CH3:38])[CH3:37])=[O:34])[CH3:28]>>[CH2:1]([O:3][C:4]([C:6]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[C:9]([Br:17])[N:8]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[C:7]=1[CH2:25][N:32]([C:33]([O:35][C:36]([CH3:37])([CH3:39])[CH3:38])=[O:34])[CH2:31][C:30]([O:29][CH2:27][CH3:28])=[O:40])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 357729Ethyl 2-((tert-butoxycarbonyl)amino)acetateHCID 68426985HCID 68426985, compound

Product 1

HCID 68426295HCID 68426295, compound

Procedure

Prepared in analogy to that of Example 1(c) from 5-bromo-2-bromomethyl-1-(4-fluoro-phenyl)-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 625 (M+Na+).

Sources & evidence

ORD record
ord-5b1b41e7a7ac4040a46586efcff7a04b
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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