4-Fluoroaniline → HCID 68429118, compound

HRID 642241Notes

Reaction equation

HRID 642241 reaction equation
C(OC(C1C=C(C2C=CC(F)=CC=2)N(C2C=CC=CC=2)C=1C)=O)C.[CH2:25]([O:27][C:28](=[O:40])[CH:29]([C:37](=O)[CH3:38])[CH2:30][C:31](=O)[C:32]([CH3:35])([CH3:34])[CH3:33])[CH3:26].[F:41][C:42]1[CH:48]=[CH:47][C:45]([NH2:46])=[CH:44][CH:43]=1>>[CH2:25]([O:27][C:28]([C:29]1[CH:30]=[C:31]([C:32]([CH3:35])([CH3:34])[CH3:33])[N:46]([C:45]2[CH:47]=[CH:48][C:42]([F:41])=[CH:43][CH:44]=2)[C:37]=1[CH3:38])=[O:40])[CH3:26]

Participants

4

Reactant 3

HCID 97314-FluoroanilineHCID 11775940Ethyl 2-acetyl-5,5-dimethyl-4-oxohexanoateHCID 143391945-(4-Fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester

Product 1

HCID 68429118HCID 68429118, compound

Procedure

Prepared in analogy to that of 5-(4-fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester from 2-Acetyl-5,5-dimethyl-4-oxo-hexanoic acid ethyl ester and 4-fluoroaniline. The title compound, ESI MS (m/z): 304 (M+H+).

Sources & evidence

ORD record
ord-b042fadb4fd049e9a00b1942ffd4ee9e
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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