Ethyl 2-((tert-butoxycarbonyl)amino)acetate → HCID 68426378, compound

HRID 642242Notes

Reaction equation

HRID 642242 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:10]([Br:11])=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[N:8]([C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)[C:7]=1[CH2:23]Br)=[O:5])[CH3:2].[CH2:25]([O:27][C:28](=[O:38])[CH2:29][NH:30][C:31]([O:33][C:34]([CH3:37])([CH3:36])[CH3:35])=[O:32])[CH3:26]>>[CH2:1]([O:3][C:4]([C:6]1[C:10]([Br:11])=[C:9]([C:12]([CH3:13])([CH3:14])[CH3:15])[N:8]([C:16]2[CH:17]=[CH:18][C:19]([F:22])=[CH:20][CH:21]=2)[C:7]=1[CH2:23][N:30]([C:31]([O:33][C:34]([CH3:35])([CH3:37])[CH3:36])=[O:32])[CH2:29][C:28]([O:27][CH2:25][CH3:26])=[O:38])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 357729Ethyl 2-((tert-butoxycarbonyl)amino)acetateHCID 68426087HCID 68426087, compound

Product 1

HCID 68426378HCID 68426378, compound

Procedure

Prepared in analogy to that of Example 1(c) from 4-bromo-2-bromomethyl-5-tert-butyl-1-(4-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 605 (M+Na+).

Sources & evidence

ORD record
ord-12b5f31a83074b2d8250dfbdc5d19fe5
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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